Genomic associations with poxvirus across divergent island populations in Berthelot's pipit.

ABSTRACT: Understanding the mechanisms and genes that enable animal populations to adapt to pathogens is important from an evolutionary, health and conservation perspective. Berthelot's pipit (Anthus berthelotii) experiences extensive and consistent spatial heterogeneity in avian pox infection pressure across its range of island populations, thus providing an excellent system with which to examine how pathogen-mediated selection drives spatial variation in immunogenetic diversity. Here, we test for evidence of genetic variation associated with avian pox at both an individual and population-level. At the individual level, we find no evidence that variation in MHC class I and TLR4 (both known to be important in recognising viral infection) was associated with pox infection within two separate populati

SUBMITTER: Sheppard EC 

PROVIDER: S-EPMC9321574 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature