How measurements affected by medication use are reported and handled in observational research: A literature review.

ABSTRACT:

Purpose

In epidemiological research, measurements affected by medication, for example, blood pressure lowered by antihypertensives, are common. Different ways of handling medication are required depending on the research questions and whether the affected measurement is the exposure, the outcome, or a confounder. This study aimed to review handling of medication use in observational research.

Methods

PubMed was searched for etiological studies published between 2015 and 2019 in 15 high-ranked journals from cardiology, diabetes, and epidemiology. We selected studies that analyzed blood pressure, glucose, or lipid measurements (whether exposure, outcome or confounder) by linear or logistic regression. Two reviewers independently recorded how medication use was handled and asse

SUBMITTER: Choi J 

PROVIDER: S-EPMC9321697 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature