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Platypnoea-orthodeoxia syndrome as an uncommon cause of dyspnoea: a literature review.

ABSTRACT: Platypnoea-orthodeoxia syndrome (POS) is an uncommon but challenging clinical condition characterised by positional dyspnoea (platypnoea) and arterial desaturation (orthodeoxia) in the upright position that improve in the supine position. Since its first description, many cases have been reported and many conditions have been associated with this syndrome. Herein, we review the clinical presentation, pathophysiology, diagnostic work-up and management of patients with POS, aiming to increase the awareness of this often misdiagnosed condition.

SUBMITTER: Lombardi M

PROVIDER: S-EPMC9321992 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Platypnoea-orthodeoxia syndrome as an uncommon cause of dyspnoea: a literature review.

Lombardi Marco M Del Buono Marco G MG Princi Giuseppe G Locorotondo Gabriella G Lombardo Antonella A Vergallo Rocco R Montone Rocco A RA Burzotta Francesco F Trani Carlo C Crea Filippo F Sanna Tommaso T

Internal medicine journal 20220404 6

Platypnoea-orthodeoxia syndrome (POS) is an uncommon but challenging clinical condition characterised by positional dyspnoea (platypnoea) and arterial desaturation (orthodeoxia) in the upright position that improve in the supine position. Since its first description, many cases have been reported and many conditions have been associated with this syndrome. Herein, we review the clinical presentation, pathophysiology, diagnostic work-up and management of patients with POS, aiming to increase the ...[more]

PMID: 34935270

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Platypnoea-orthodeoxia syndrome: novel cause for a known condition.

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Platypnoea-orthodeoxia syndrome induced by short-term weight loss: a case series.

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Platypnoea-orthodeoxia syndrome after percutaneous treatment of ruptured sinus Valsalva complicated by SARS-Cov-2 pneumonia: a case report.

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