Resting-State Brain Variability in Youth With Attention-Deficit/Hyperactivity Disorder.

ABSTRACT: In this study, we sought to determine the nature of the abnormality in resting-state default mode network (DMN) activation and explore its correlation with functional connectivity in attention-deficit/hyperactivity disorder (ADHD). We obtained resting-state functional magnetic resonance images of youth with ADHD and typically developing counterparts from the publicly available ADHD-200 database. We used data from Peking University (232 scans) and New York University (172 scans); the scan repetition time was 2 s for both data collection sites. We applied generalized estimating equations to estimate the variability of the averaged blood-oxygen-level-dependent (BOLD) time series extracted from the DMN at rest. We performed network-based statistics to determine the association between the obse

SUBMITTER: Hong SB 

PROVIDER: S-EPMC9322108 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature