Higher Levels of Serum Uric Acid Have a Significant Association with Lower Incidence of Lower Urinary Tract Symptoms in Healthy Korean Men.

ABSTRACT: Gout has been correlated with the risk of incident benign prostatic hyperplasia. In line with increasing prevalence of hyperuricemia, the aim of this study was to investigate the relationship between serum uric acid (SUA) level and the incidence of lower urinary tract symptoms (LUTS) among clinically healthy middle-aged men. We performed a cohort study in 101,091 Korean men without LUTS at baseline who completed health checkups between 2011 and 2016. LUTS were evaluated using the International Prostate Symptom Score, where a score ≥ 8 was defined as significant LUTS. Men were divided into six groups according to their SUA levels in mg/dL (<5.5, 5.5-6.4, 6.5-7.4, 7.5-8.4, 8.5-9.4, and ≥9.5). Throughout the follow-up-encompassing a total of 358,982.6 person years-13,424 people had signifi

SUBMITTER: Hwang J 

PROVIDER: S-EPMC9322789 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature