Synthesis of Carvacrol Derivatives as Potential New Anticancer Agent against Lung Cancer.

ABSTRACT: Lung cancer remains a major public health concern among all cancer diseases due to the toxicity and side-effects of the available commercially synthesized drugs. Natural product-derived synthesized anticancer drugs are now of promising interest to fight against cancer death. Carvacrol is a major component of most essential oil-bearing plants with potential pharmacological activity, especially against various cancer cell lines. Among the other organometallic compounds, copper complexes have been reported to be effective anticancer agents against various cancer cell lines, especially lung and leukemia cancers, due to the nontoxic nature of copper in normal cells since it is an endogenic metal. In this study, we synthesized three carvacrol derivatives, i.e., carvacrol aldehyde, Schiff base, a

SUBMITTER: Bansal A 

PROVIDER: S-EPMC9323284 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature