Exploring Sea Lice Vaccines against Early Stages of Infestation in Atlantic Salmon (Salmo salar).

ABSTRACT: The sea louse Caligus rogercresseyi genome has opened the opportunity to apply the reverse vaccinology strategy for identifying antigens with potential effects on lice development and its application in sea lice control. This study aimed to explore the efficacy of three sea lice vaccines against the early stage of infestation, assessing the transcriptome modulation of immunized Atlantic salmon. Therein, three experimental groups of Salmo salar (Atlantic salmon) were vaccinated with the recombinant proteins: Peritrophin (prototype A), Cathepsin (prototype B), and the mix of them (prototype C), respectively. Sea lice infestation was evaluated during chalimus I-II, the early-infective stages attached at 7-days post infestation. In parallel, head kidney and skin tissue samples we

SUBMITTER: Casuso A 

PROVIDER: S-EPMC9324576 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature