Symptom patterns in the daily life of PSC patients.

ABSTRACT:

Background & aims

Patients with primary sclerosing cholangitis (PSC) may suffer from complaints such as pruritus, right upper abdominal quadrant pain (RUQ-A) and fatigue. However, the severity of these complaints, daily and/or seasonal patterns and other factors of influence in PSC are largely unknown. The aim of this study is to assess daily symptoms and patterns thereof in PSC patients in their natural setting.

Methods

A mobile application was designed according to the experience sampling method. Push notifications with a response time of max 4 h were sent during tiers of 3 months. Questions comprised VAS scales on degree of pruritus, fatigue, RUQ-A, time of the day these symptoms were worst, as well as time of intake of medication. Linear mixed modelling was used to ident

SUBMITTER: van Munster KN 

PROVIDER: S-EPMC9325051 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature