RETRACTED: Environmental Impact of Pharmaceutical Pollutants: Synergistic Toxicity of Ivermectin and Cypermethrin.

ABSTRACT: Veterinary antiparasitic pharmaceuticals as well as pesticides have been detected in surface waters, and they may cause several toxic effects in this environmental compartment. In the present study, we evaluated the toxicity after exposure of different concentration of ivermectin (IVM; 50, 100, and 200 μg L^-1) and cypermethrin (CYP; 5, 10, and 25 μg L^-1) and the combination of these two compounds at non-toxic concentration (IVM 100 + CYP 5 μg L^-1) in zebrafish embryos. Combination of IVM at 100 μg L^-1 with CYP at 5 μg L^-1 exposure induced hatching delay and malformations at 96 hpf in zebrafish larvae as well as significant induction of cell death in zebrafish larvae. At the same time, the two single concentrations of IVM and CYP did no

SUBMITTER: Paola DD 

PROVIDER: S-EPMC9325130 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature