Mortality among patients with low-grade follicular lymphoma: A binational retrospective analysis.

ABSTRACT:

Background

The life expectancy of patients with follicular lymphoma (FL) has improved considerably since the introduction of rituximab. This study examined the proportion of deaths from progressive lymphoma and the impact of FL on survival compared with that in the general population.

Methods

Altogether, 749 patients with grades 1 and 2 FL in 9 institutions between 1997 and 2016 were enrolled. Competing risk models were used to estimate the cumulative incidences of deaths from progressive lymphoma and from other reasons. Excess mortality was analyzed with respect to the corresponding background populations standardized for age and sex using the excess mortality model based on the penalized spline approach.

Results

The median follow-up duration was 69 months (range, 0-

SUBMITTER: Rajamaki A 

PROVIDER: S-EPMC9325396 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature