Suppression of influenza virus infection by rhinovirus interference - at the population, individual and cellular levels.

ABSTRACT:

Background

Influenza virus (IV) and the rhinovirus (RV) are the two most common circulating respiratory viruses circulating. Natural viral interference has been suggested between them. The effect of such at the population level has been described in temperate region, while its effect at the individual and cellular levels warrants further validation. In this study, we described the respiratory virus epidemiology and the co-infection landscape in the hospitalized population and investigated the distinct molecular pathways involved in the inhibition of virus replication.

Methods

Nasopharyngeal aspirates (NPAs) collected from patients during 2015 to 2019 were examined for the presence of respiratory viruses. The correlation of the monthly prevalence between all the tested respir

SUBMITTER: Tao KP 

PROVIDER: S-EPMC9325905 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature