Prognosis and persistence of smell and taste dysfunction in patients with covid-19: meta-analysis with parametric cure modelling of recovery curves.

ABSTRACT:

Objective

To clarify in patients with covid-19 the recovery rate of smell and taste, proportion with persistent dysfunction of smell and taste, and prognostic factors associated with recovery of smell and taste.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Scopus, Cochrane Library, and medRxiv from inception to 3 October 2021.

Review methods

Two blinded reviewers selected observational studies of adults (≥18 years) with covid-19 related dysfunction of smell or taste. Descriptive prognosis studies with time-to-event curves and prognostic association studies of any prognostic factor were included.

Data extraction and synthesis

Two reviewers extracted data, evaluated study bias using QUIPS, and appraised evidence quality using GR

SUBMITTER: Tan BKJ 

PROVIDER: S-EPMC9326326 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature