Changes in Brain Electrical Activity after Transient Middle Cerebral Artery Occlusion in Rats.

ABSTRACT: Objectives. Ischemic stroke is a leading cause of death and disability worldwide. To search for new therapeutic and pharmacotherapeutic strategies, numerous models of this disease have been proposed, the most popular being transient middle cerebral artery occlusion. Behavioral and sensorimotor testing, biochemical, and histological methods are traditionally used in conjunction with this model to assess the effectiveness of potential treatment options. Despite its wide overall popularity, electroencephalography/electrocorticography is quite rarely used in such studies. Materials and methods. In the present work, we explored the changes in brain electrical activity at days 3 and 7 after 30- and 45-min of transient middle cerebral artery occlusion in rats. Results. Cerebr

SUBMITTER: Sysoev YI 

PROVIDER: S-EPMC9326608 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature