Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study).

ABSTRACT:

Background

Prior research on cognitive and functional outcomes after coronary artery bypass graft (CABG) surgery has largely explored these two domains in isolation. In this study, we assess baseline depression and cognition as risk factors for decline in the Clinical Dementia Rating Sum-of-Boxes (CDR-SB) 1 month post-CABG surgery, which a combined measure of cognition and function.

Design

The Neuropsychiatric Outcomes After Heart Surgery study is a prospective observational cohort study.

Setting

A tertiary care, academic center.

Participants

Of a total study sample of 148 patients undergoing CABG surgery, 124 (83.8%) completed 1-month follow-up assessment. Mean age was 66.3, 32 (25.8%) female and 112 (90.3%) White.

Measurements

Cognition, function, and

SUBMITTER: Oldham MA 

PROVIDER: S-EPMC9326959 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature