Risk factors for cognitive decline in type 2 diabetes mellitus patients in Brazil: a prospective observational study.

ABSTRACT:

Background

Type 2 Diabetes Mellitus (T2DM) patients are twice as likely to develop dementia. The study's goal was to evaluate cognitive performance and risk factors for cognitive decline in this population.

Methods

Prospective observational study was conducted with 400 T2DM adults, of whom, during routine baseline and follow-up appointments, had socio-demographic, clinical, and laboratory data collected, and underwent physical examination, screening for depression symptoms (Patient Health Questionaire-9-PHQ-9), and cognitive tests: Mini-Mental State Examination (MMSE), Semantic Verbal Fluency Test, Trail Making Test A/B, and Word Memory Tests. Each cognitive test score was converted to a z-score and its average resulted in a new variable called Global Cognitive z-Score [GCS(

SUBMITTER: de Almeida Faria ACR 

PROVIDER: S-EPMC9327152 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature