Allostatic load as predictor of mortality: a cohort study from Lolland-Falster, Denmark.

ABSTRACT:

Objectives

The purposes of the present study were to determine the association between (1) 10 individual biomarkers and all-cause mortality; and between (2) allostatic load (AL), across three physiological systems (cardiovascular, inflammatory, metabolic) and all-cause mortality.

Design

Prospective cohort study.

Setting

We used data from the Lolland-Falster Health Study undertaken in Denmark in 2016-2020 and used data on systolic blood pressure (SBP) and diastolic blood pressure (DBP), pulse rate (PR), waist-hip ratio (WHR) and levels of low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), triglycerides, glycated haemoglobin A1c (HbA1c), C-reactive protein (CRP) and serum albumin. All biomarkers were divided into quartiles with hi

SUBMITTER: Bruun-Rasmussen NE 

PROVIDER: S-EPMC9327798 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature