Epidemiological studies of CT scans and cancer risk: the state of the science.

ABSTRACT: 20 years ago, 3 manuscripts describing doses and potential cancer risks from CT scans in children raised awareness of a growing public health problem. We reviewed the epidemiological studies that were initiated in response to these concerns that assessed cancer risks from CT scans using medical record linkage. We evaluated the study methodology and findings and provide recommendations for optimal study design for new efforts. We identified 17 eligible studies; 13 with published risk estimates, and 4 in progress. There was wide variability in the study methodology, however, which made comparison of findings challenging. Key differences included whether the study focused on childhood or adulthood exposure, radiosensitive outcomes (e.g. leukemia, brain tumors) or all cancers, the expos

SUBMITTER: Berrington de Gonzalez A 

PROVIDER: S-EPMC9328069 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature