Novel protein carrier system based on cyanobacterial nano-sized extracellular vesicles for application in fish.

ABSTRACT: Aquaculture has been one of the fastest-growing food industry sectors, expanding at the pace of consumers' demands. To promote safe and effective fish growth performance strategies, and to stimulate environmentally friendly solutions to protect fish against disease outbreaks, new approaches are needed to safeguard fish welfare, as well as farmers and consumers interests. Here, we tested the use of cyanobacterial extracellular vesicles (EVs) as a novel nanocarrier system of heterologous proteins for applications in fish. We started by incubating zebrafish larvae with Synechocystis sp. PCC6803 EVs, isolated from selected mutant strains with different cell envelope characteristics. Results show that Synechocystis EVs are biocompatible with fish larvae, regardless of their structural compositi

SUBMITTER: Matinha-Cardoso J 

PROVIDER: S-EPMC9328742 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature