A Novel Serum Biomarker Model to Discriminate Aortic Dissection from Coronary Artery Disease.

ABSTRACT:

Background

The misdiagnosis of aortic dissection (AD) can lead to a catastrophic prognosis. There is currently a lack of stable serological indicators with excellent efficacy for the differential diagnosis of AD and coronary artery disease (CAD). A recent study has shown an association between AD and iron metabolism. Thus, we investigated whether iron metabolism could discriminate AD from CAD.

Methods

This retrospective and multicenter cross-sectional study investigated the efficacy of biomarkers of iron metabolism for the differential diagnosis of AD. We collected biomarkers of iron metabolism, liver function, kidney function, and other biochemistry test, and further, logistic regression analysis was applied.

Results

Between Oct. 8, 2020, and Mar. 1, 2021, we recruit

SUBMITTER: Lu P 

PROVIDER: S-EPMC9329023 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature