Elevated Blood S100B Levels in Patients With Migraine: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

In recent years, a growing number of researches indicate that S100B may act in migraine, but the relationship between S100B and migraine remains controversial. Therefore, the current study aimed to perform a meta-analysis to quantitatively summarize S100B levels in migraine patients.

Methods

We used Stata 12.0 software to summarize eligible studies from PubMed, EMBASE, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), and Wanfang databases. We applied standardized mean differences (SMDs) with 95% confidence intervals (95%CIs) to appraise the association between S100B and migraine.

Results

The combined results of nine case-control studies indicated that compared with healthy controls, overall migraine patients had significantl

SUBMITTER: Chu C 

PROVIDER: S-EPMC9329586 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature