Comparative Analysis of Epidemiological and Clinical Characteristics Between Invasive Candida Infection versus Colonization in Critically Ill Patients in a Tertiary Hospital in Anhui, China.

ABSTRACT:

Objective

Invasive infections due to Candida spp. have unique epidemiology, strain distribution, antimicrobial susceptibility, and clinical features. This study aimed to compare and evaluate these characteristic variables between invasive Candida infection and colonization of critically ill patients in local China to potentially improve differential diagnosis and therapy.

Methods

A total of 193 critically ill patients were recruited and followed up for the study, and 133 Candida isolates were obtained from invasive Candida-infected or -colonized subjects. The strains were identified to species level through matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry, assisted by DNA sequencing. Candida susceptibility to com

SUBMITTER: Xia J 

PROVIDER: S-EPMC9329706 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature