Size-Dependent Spontaneous Separation of Colloidal Particles in Sub-Microliter Suspension by Cations.

ABSTRACT: Great efforts have been made to separate micro/nanoparticles in small-volume specimens, but it is a challenge to achieve the simple, maneuverable and low-cost separation of sub-microliter suspension with large separation distances. By simply adding trace amounts of cations (Mg²⁺/Ca²⁺/Na⁺), we experimentally achieved the size-dependent spontaneous separation of colloidal particles in an evaporating droplet with a volume down to 0.2 μL. The separation distance was at a millimeter level, benefiting the subsequent processing of the specimen. Within only three separating cycles, the mass ratio between particles with diameters of 1.0 μm and 0.1 μm can be effectively increased to 13 times of its initial value. A theoretical analysis indicates that this spontaneous

SUBMITTER: Sheng S 

PROVIDER: S-EPMC9329736 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature