An Electromechanical Lab-on-a-Chip Platform for Colorimetric Detection of Serum Creatinine.

ABSTRACT: Chronic kidney disease (CKD) is a high-cost disease that affects approximately one in ten people globally, progresses rapidly, results in kidney failure or dialysis, and triggers other diseases. Although clinically used serum creatinine tests are used to evaluate kidney functions, these tests are not suitable for frequent and regular control at-home settings that obstruct the regular monitoring of kidney functions, improving CKD management with early intervention. This study introduced a new electromechanical lab-on-a-chip platform for point-of-care detection of serum creatinine levels using colorimetric enzyme-linked immunosorbent assay (ELISA). The platform was composed of a chip containing microreservoirs, a stirring bar coated with creatinine-specific antibodies, and a phone to detect

SUBMITTER: Karakuzu B 

PROVIDER: S-EPMC9330075 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature