Impaired Vitamin D Metabolism in Hospitalized COVID-19 Patients.

ABSTRACT: There is increasing data regarding the association between vitamin D and COVID-19. This study aimed to reveal the alterations of vitamin D metabolism in the setting of COVID-19. We examined 119 adult COVID-19 inpatients and 44 apparently healthy adult individuals with similar serum 25OH-D₃ levels as a reference group. The assessment included serum biochemical parameters (total calcium, albumin, phosphorus, creatinine), parathyroid hormone (PTH), vitamin D-binding protein (DBP), vitamin D metabolites (25OH-D₃, 25OH-D₂, 1,25(OH)₂D₃, 3-epi-25OH-D₃, 24,25(OH)₂D₃ and D₃) and free 25OH-D. COVID-19 patients had in general very low vitamin D levels (median 25OH-D₃ equals 10.8 ng/mL), accom

SUBMITTER: Povaliaeva A 

PROVIDER: S-EPMC9330123 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature