Serum Vitamin D Concentrations, Time to Pregnancy, and Pregnancy Outcomes among Preconception Couples: A Cohort Study in Shanghai, China.

ABSTRACT:

Background

The role of vitamin D in reproductive health is still unclear. This study aimed to assess the effect of serum 25-hydroxyvitamin D (25(OH)D), among preconception couples, on fecundity, and the associations between 25(OH)D concentrations before and during pregnancy, and pregnancy outcomes.

Methods

200 preconception couples attempting to conceive were recruited and were followed-up until childbirth. Time to pregnancy was collected via telephone every two months or obtained via a questionnaire during pregnancy. Blood samples were collected to measure serum 25(OH)D levels from both partners at enrollment and from women during the second and third trimester of pregnancy.

Results

Couples had higher conception rates within six months (adjusted odds ratio (aOR): 3.7

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9330297 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature