Gestational diabetes mellitus and offspring's carotid intima-media thickness at birth: MySweetHeart Cohort study.

ABSTRACT:

Objective

Hyperglycaemia during pregnancy is associated with cardiometabolic risks for the mother and the offspring. Mothers with gestational diabetes mellitus (GDM) have signs of subclinical atherosclerosis, including increased carotid intima-media thickness (CIMT). We assessed whether GDM is associated with increased CIMT in the offspring at birth.

Design and setting

MySweetHeart Cohort is a prospective cohort study conducted in Switzerland.

Participants, exposure and outcome measures

This work included pregnant women with and without GDM at 24-32 weeks of gestation and their singleton live-born offspring with data on the primary outcome of CIMT. GDM was diagnosed based on the criteria of the International Association of Diabetes and Pregnancy Study Groups. Offsprin

SUBMITTER: Epure AM 

PROVIDER: S-EPMC9330339 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature