Microbial Spectrum and Antibiotic Resistance in Patients Suffering from Penetrating Crohn's Disease.

ABSTRACT: Intraabdominal abscess formation occurs in up to 30% of patients suffering from Crohn´s disease (CD). While international guidelines recommend a step-up approach with a combination of empiric antibiotic therapy and percutaneous drainage to delay or even avoid surgery, evidence about microbial spectrum in penetrating ileitis is sparse. We retrospectively assessed outcomes of 46 patients with terminal penetrating Ileitis where microbial diagnostics have been performed and compared microbial spectrum and antibiotic resistance profile of CD patients with patients suffering from diverticulitis with intraabdominal abscess formation. In both groups, the most frequently isolated pathogen was the gram-negative bacterium E.coli belonging to the family of Enterobacterales. However, over

SUBMITTER: Kusan S 

PROVIDER: S-EPMC9330589 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature