The Effect of Low Glycemic Index Mediterranean Diet and Combined Exercise Program on Metabolic-Associated Fatty Liver Disease: A Joint Modeling Approach.

ABSTRACT:

Background

Excessive caloric intake and reduced energy expenditure are associated with the onset of metabolic-associated fatty liver disease (MAFLD). The aim of this study was to probe the benefits of a low glycemic index Mediterranean diet (LGIMD) and a combined exercise program (CEP) on MAFLD by monitoring the clinical process through anthropometric measurement, body mass index (BMI), and specific biomarkers, such as the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR).

Methods

The study was conducted at the National Institute of Gastroenterology, 'S. de Bellis', Italy. Subjects were invited to join the study for 12 months.

Results

54 participants were enrolled. Joint modeling of longitudinal and time-to-event data was applied. Overall, a statistically

SUBMITTER: Curci R 

PROVIDER: S-EPMC9330790 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature