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Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic Insights.

ABSTRACT: Prostate cancer (PCa) is the leading cause of cancer death in men, and its treatment is commonly associated with severe adverse effects. Thus, new treatment modalities are required. In this context, natural compounds have been widely explored for their anti-PCa properties. Aquatic organisms contain numerous potential medications. Anticancer peptides are less toxic to normal cells and provide an efficacious treatment approach via multiple mechanisms, including altered cell viability, apoptosis, cell migration/invasion, suppression of angiogenesis and microtubule balance disturbances. This review sheds light on marine peptides as efficacious and safe therapeutic agents for PCa.

SUBMITTER: Ahmed S

PROVIDER: S-EPMC9330892 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic Insights.

Ahmed Salman S Alam Waqas W Jeandet Philippe P Aschner Michael M Alsharif Khalaf F KF Saso Luciano L Khan Haroon H

Marine drugs 20220722 8

Prostate cancer (PCa) is the leading cause of cancer death in men, and its treatment is commonly associated with severe adverse effects. Thus, new treatment modalities are required. In this context, natural compounds have been widely explored for their anti-PCa properties. Aquatic organisms contain numerous potential medications. Anticancer peptides are less toxic to normal cells and provide an efficacious treatment approach via multiple mechanisms, including altered cell viability, apoptosis, c ...[more]

PMID: 35892934

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