Antifungal Activity of Select Essential Oils against Candida auris and Their Interactions with Antifungal Drugs.

ABSTRACT: Candida auris is an emerging fungal pathogen that commonly causes nosocomial blood infections in the immunocompromised. Several factors make this pathogen a global threat, including its misidentification as closely related species, its ability to survive for weeks on fomites, and its resistance to commonly prescribed antifungal drugs, sometimes to all three classes of systemic antifungal drugs. These factors demonstrate a need for the development of novel therapeutic approaches to combat this pathogen. In the present study, the antifungal activities of 21 essential oils were tested against C. auris. Several essential oils were observed to inhibit the growth and kill C. auris, Candida lusitaniae, and Saccharomyces cerevisiae when in direct contact and at c

SUBMITTER: Parker RA 

PROVIDER: S-EPMC9331469 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature