Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study.

ABSTRACT:

Background

It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact of longitudinal patterns of TyG on the stroke risk in hypertensive patients is still unknown. Hence, this study aimed to investigate the association between TyG index trajectory and stroke risk among hypertensive patients.

Methods

This prospective study included 19,924 hypertensive patients from the Kailuan Study who underwent three waves survey and were free of myocardial infarction, cancer and stroke before or during 2010. The TyG index was calculated as ln [fasting triglyceride (mg/dL) × fasting plasma glucose (mg/dL)/2], and latent mixed modelling was use

SUBMITTER: Huang Z 

PROVIDER: S-EPMC9331781 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature