Systematic Analysis of Long Non-Coding RNA Genes in Nonalcoholic Fatty Liver Disease.

ABSTRACT: The largest solid organ in humans, the liver, performs a variety of functions to sustain life. When damaged, cells in the liver can regenerate themselves to maintain normal liver physiology. However, some damage is beyond repair, which necessitates liver transplantation. Increasing rates of obesity, Western diets (i.e., rich in processed carbohydrates and saturated fats), and cardiometabolic diseases are interlinked to liver diseases, including non-alcoholic fatty liver disease (NAFLD), which is a collective term to describe the excess accumulation of fat in the liver of people who drink little to no alcohol. Alarmingly, the prevalence of NAFLD extends to 25% of the world population, which calls for the urgent need to understand the disease mechanism of NAFLD. Here, we performed secondary

SUBMITTER: Ilieva M 

PROVIDER: S-EPMC9332188 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature