Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach.

ABSTRACT: Aedes aegypti is the main vector that transmits viral diseases such as dengue, hemorrhagic dengue, urban yellow fever, zika, and chikungunya. Worldwide, many cases of dengue have been reported in recent years, showing significant growth. The best way to manage diseases transmitted by Aedes aegypti is to control the vector with insecticides, which have already been shown to be toxic to humans; moreover, insects have developed resistance. Thus, the development of new insecticides is considered an emergency. One way to achieve this goal is to apply computational methods based on ligands and target information. In this study, sixteen compounds with acceptable insecticidal activities, with 100% larvicidal activity at low concentrations (2.0 to 0.001 mg·L−1), were selected from the literature. T

SUBMITTER: Da Costa GV 

PROVIDER: S-EPMC9332482 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature