The Epidemiology of Biliary Atresia: Exploring the Role of Developmental Factors on Birth Prevalence.

ABSTRACT:

Objective

To identify key epidemiologic factors relevant to fetal development that are associated with biliary atresia.

Study design

This population-based registry study examined infants born in Texas between 1999 and 2014. Epidemiologic data relevant to fetal development were compared between cases of biliary atresia identified in the Texas Birth Defects Registry (n = 305) vs all live births (n = 4 689 920), and Poisson regression was used to calculate prevalence ratios (PRs) and 95% CIs.

Results

The prevalence of biliary atresia over the study period was 0.65 per 10 000 live births. Biliary atresia was positively associated with female sex (adjusted PR, 1.68; 95% CI, 1.33-2.12), delivery before 32-37 weeks of gestation (adjusted PR, 1.64; 95% CI, 1.18-2.29), deliver

SUBMITTER: Cavallo L 

PROVIDER: S-EPMC9332904 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature