Evaluating the appropriateness of laboratory testing and antimicrobial use in South African children hospitalized for community-acquired infections.

ABSTRACT:

Introduction

Community acquired infection (CAI) is the leading indication for paediatric hospitalization in South Africa.

Methods

We conducted secondary data analysis of prospective, consecutive paediatric admissions to Tygerberg Hospital (May 2015-November 2015). Clinical characteristics, admission diagnosis, appropriateness of diagnostic tests, use of antimicrobial prescriptions, hospital outcome and costs were analyzed.

Results

CAI episodes were documented in (364/451; 81%) children admitted to the general paediatric ward; median age 4.8 months (Interquartile range, IQR, 1.5-17.5) and weight 5.4kg (IQR, 3.6-9.0). Male gender predominated (210/364; 58%), and Human Immunodeficiency Virus infection prevalence was 6.0% (22/364). Common CAI types included respiratory tr

SUBMITTER: Mapala L 

PROVIDER: S-EPMC9333228 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature