An updated systematic review and meta-analysis of fecal microbiota transplantation for the treatment of ulcerative colitis.

ABSTRACT:

Background

Fecal microbiota transplantation (FMT) as a promising therapy for ulcerative colitis (UC) remains controversial. We conducted a systematic review and meta-analysis to assess the efficiency and safety of FMT as a treatment for UC.

Methods

The target studies were identified by searching PubMed, EMBASE, the Cochrane Library, Web of Science, and ClinicalTrials and by manual supplementary retrieval. We conducted a general review and quantitative synthesis of included studies. We used the RevMan and Stata programs in the meta-analysis. The outcomes were total remission, clinical remission, steroid-free remission, and serious adverse events. We also performed subgroup analyses based on different populations.

Results

A total of 34 articles were included in the gene

SUBMITTER: Huang T 

PROVIDER: S-EPMC9333500 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature