Meta-Prism 2.0: Enabling algorithm and web server for ultra-fast, memory-efficient, and accurate analysis among millions of microbial community samples.

ABSTRACT:

Background

Microbial community samples have been accumulating at a speed faster than ever, with hundreds of thousands of samples been sequenced each year. Mining such a huge amount of multisource heterogeneous data is becoming an increasingly difficult challenge, so efficient and accurate compare and search of samples is in urgent need: faced with millions of samples in the data repository, traditional sample comparison and search approaches fall short in speed and accuracy.

Findings

Here we proposed Meta-Prism 2.0, a microbial community sample analysis method that has pushed the time and memory efficiency to a new limit without compromising accuracy. Based on sparse data structure, time-saving instruction pipeline, and SIMD optimization, Meta-Prism 2.0 has enabled ultra-fas

SUBMITTER: Kang K 

PROVIDER: S-EPMC9334027 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature