Advancing precision medicines for ocular disorders: Diagnostic genomics to tailored therapies.

ABSTRACT: Successful sequencing of the human genome and evolving functional knowledge of gene products has taken genomic medicine to the forefront, soon combining broadly with traditional diagnostics, therapeutics, and prognostics in patients. Recent years have witnessed an extraordinary leap in our understanding of ocular diseases and their respective genetic underpinnings. As we are entering the age of genomic medicine, rapid advances in genome sequencing, gene delivery, genome surgery, and computational genomics enable an ever-increasing capacity to provide a precise and robust diagnosis of diseases and the development of targeted treatment strategies. Inherited retinal diseases are a major source of blindness around the world where a large number of causative genes have been identified, paving t

SUBMITTER: Panikker P 

PROVIDER: S-EPMC9334564 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature