All-cause and cardiovascular mortality in relation to lung function in the full range of distribution across four Eastern European cohorts.

ABSTRACT: It is unclear whether the dose-response relationship between lung function and all-cause and cardiovascular mortality in the Central and Eastern European populations differ from that reported in the Western European and American populations. We used the prospective population-based HAPIEE cohort that includes randomly selected people with a mean age of 59 ± 7.3 years from population registers in Czech, Polish, Russian and Lithuanian urban centres. The baseline survey in 2002-2005 included 36,106 persons of whom 24,944 met the inclusion criteria. Cox proportional hazards models were used to estimate the dose-response relationship between lung function defined as FEV1 divided by height cubed and all-cause and cardiovascular mortality over 11-16 years of follow-up. Mortality rate increased in

SUBMITTER: Sarycheva T 

PROVIDER: S-EPMC9334616 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature