Microwave ablation vs. surgical resection for treatment naive hepatocellular carcinoma within the Milan criteria: a follow-up of at least 5 years.

ABSTRACT:

Objective

Thermal ablation poses challenges in the surgical resection (SR) of small hepatocellular carcinoma (HCC), and its therapeutic outcomes for larger lesions remain debated.

Methods

This retrospective study evaluated 729 patients with HCC meeting the Milan criteria, who were treated with curative SR or microwave ablation (MWA) between 2008 and 2014. Overall survival (OS), cancer-specific survival (CSS), disease-free survival (DFS), and local tumor progression (LTP) were compared after propensity score matching (PSM). Co-variates associated with OS, CSS, LTP, and DFS were identified. The risk of death and tumor progression were compared.

Results

During the median follow-up of 78.6 months, 253 patients were included in each group after PSM. For tumors ≤ 3.0 cm and

SUBMITTER: Dou J 

PROVIDER: S-EPMC9334764 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature