An imaging mass cytometry immunophenotyping panel for non-human primate tissues.

ABSTRACT: It has recently become clear that spatial organization contributes to cellular function and that expanding our knowledge on cellular organization is essential to further our understanding of processes in health and disease. Imaging mass cytometry enables high dimensional imaging of tissue while preserving spatial context and is therefore a suitable tool to unravel spatial relationships between cells. As availability of human tissue collected over the course of disease or infection is limited, preclinical models are a valuable source of such material. Non-human primate models are used for translational research as their anatomy, physiology and immune system closely resemble those of humans due to close evolutionary proximity. Tissue from non-human primate studies is often preserved large ar

SUBMITTER: Niewold P 

PROVIDER: S-EPMC9334813 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature