Assessment and Diagnosis of Down Syndrome Regression Disorder: International Expert Consensus.

ABSTRACT:

Objective

To develop standardization for nomenclature, diagnostic work up and diagnostic criteria for cases of neurocognitive regression in Down syndrome.

Background

There are no consensus criteria for the evaluation or diagnosis of neurocognitive regression in persons with Down syndrome. As such, previously published data on this condition is relegated to smaller case series with heterogenous data sets. Lack of standardized assessment tools has slowed research in this clinical area.

Methods

The authors performed a two-round traditional Delphi method survey of an international group of clinicians with experience in treating Down syndrome to develop a standardized approach to clinical care and research in this area. Thirty-eight potential panelists who had either previ

SUBMITTER: Santoro JD 

PROVIDER: S-EPMC9335003 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature