Effect of oral administration of GABA on thermoregulation in athletes during exercise in cold environments: A preliminary study.

ABSTRACT:

Background

γ-aminobutyric acid (GABA), a common ingredient in sports supplements and other health products, regulates body temperature in the preoptic area and anterior hypothalamus (PO/AH). To date, no study has examined the effect of GABA on thermoregulation during exercise in humans in a cold temperature environment (11 ± 0.3°C, 45% ± 2% relative humidity).

Methods

We performed a randomized, double-blind study. Ten trained male athletes consumed either a drink (3 ml/kg weight) containing GABA (1,000 mg, trial G) or an equivalent amount of placebo drink (trial C) before exercise. They rested for 20 min and then cycled at 60% of maximum output power for 40 min, pedaling at 60 rpm, and recovered for 20 min. Core temperature (T_c), skin temperature (upper arm, chest

SUBMITTER: Wang H 

PROVIDER: S-EPMC9335056 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature