Seizures in children undergoing extracorporeal membrane oxygenation: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To investigate the incidence of seizures and short-term mortality associated with seizures in children undergoing extracorporeal membrane oxygenation (ECMO).

Methods

PubMed, Embase, and Web of Science were searched from inception to September 2021. Study quality was assessed using the Newcastle-Ottawa Scale. Random effects meta-analysis was conducted.

Results

Fourteen studies met the inclusion criteria for quantitative meta-analysis. The cumulative estimate of seizure incidence was 15% (95% CI: 12-17%). Studies using electroencephalography reported a higher incidence of seizures compared with those using electro-clinical criteria (19% vs. 9%, P = 0.034). Furthermore, 75% of seizures were subclinical. Children receiving extracorporeal cardiopulmonary resusci

SUBMITTER: Lin G 

PROVIDER: S-EPMC9336161 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature