Inflammatory biomarkers and risk of cardiovascular events in patients undergoing coronary angiography.

ABSTRACT:

Background

Inflammation, measured by traditional biomarkers such as C-reactive protein, has been linked to cardiovascular (CV) events. Recent technological advancement has allowed for measuring larger numbers of inflammatory biomarkers. A contemporary evaluation with established and novel biomarkers of inflammation is needed.

Methods

1,090 individuals who underwent coronary angiography were enrolled. Twenty-four inflammatory biomarkers were collected prior to angiography. Unsupervised machine learning cluster analyses determined unique patterns of inflammatory biomarkers. Cox proportional hazard regression assessed both association of inflammatory biomarker clusters and individual biomarker associations with major adverse cardiovascular events (MACE; non-fatal myocardial inf

SUBMITTER: Mohebi R 

PROVIDER: S-EPMC9336200 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature