Comprehensive silk gland multi-omics comparison illuminates two alternative mechanisms in silkworm heterosis.

ABSTRACT: Heterosis is a common phenomenon in plants and animals with diverse underlying mechanisms. Here, we applied two widely used silkworm hybrid systems and performed multi-omics analysis to identify possible intrinsic associations between different hybrid strategies and epigenetic mechanisms with silkworm heterosis. We found significant differences in the silk gland transcriptomic landscape between the two systems, including differentially expressed genes and expression patterns in the hybrid offspring compared to their parents. In the quaternary hybrid system, hybrid vigor was primarily due to up-regulated genes and the parent-dominant up-regulated expression pattern, involving multiple transport processes, cellular nitrogen compound catabolism, glucose metabolism, and tricarboxylic acid cycl

SUBMITTER: Xu H 

PROVIDER: S-EPMC9336454 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature