Effectiveness and safety of PRP on persistent olfactory dysfunction related to COVID-19.

ABSTRACT:

Introduction

Olfactory dysfunction (OD) is a well know symptom of coronavirus disease 2019 (COVID-19), accounting for 48 to 85% of patients. In 1 to 10% of cases, patients develop a chronic olfactory dysfunction (COD), lasting more than 6 months. Recently, platelet-rich plasma (PRP) was used in patients with non-COVID-19 COD and authors reported encouraging results.

Methods

In the present study, we investigated the usefulness and safety of PRP injection in 56 patients with COVID-19 COD by the Sniffing Stick test (TDI score) and a linker-scale from 0 (none) to 3 (strong) and we compare the result to a control group.

Results

At 1 month post-PRP injection, the mean TDI scores significantly improved by 6.7 points in the PRP group (p < 0,001), the mean self-assessment of i

SUBMITTER: Steffens Y 

PROVIDER: S-EPMC9336533 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature