Anatomic location of colorectal cancer presents a new paradigm for its prognosis in African American patients.

ABSTRACT: Among all racial groups in the U.S., African Americans (AA) have the highest incidence of and mortality from colorectal cancer (CRC). Although socioeconomic factors, as the major contributors to racial disparity of CRC, have been widely investigated, there is a dearth of information germane to understanding its biological basis. To better elucidate the clinicopathologic features we extracted demographic, clinical, pathologic and molecular features of 500 consecutive cases of CRC diagnosed at our institution which has an AA-predominant patient population (75% of all patients). We compared data from our AA patients with those of white patients both from our institution and from SEER and the published literature for meaningful comparison. AA patients were more likely to be at an advanced dise

SUBMITTER: Wang D 

PROVIDER: S-EPMC9337663 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature