Japanese encephalitis virus persists in the human reproductive epithelium and porcine reproductive tissues.

ABSTRACT: Japanese encephalitis virus (JEV) is the emerging and geographically expanding flavivirus and the major causative agent of encephalitis in humans in Asia. There are risks of JEV introduction into the Americas given a large population of amplifying hosts-pigs and wild boars, and insect vectors-Culex mosquitoes. There are emerging concerns about vector-free ways of flavivirus transmission, for example sexual and transplacental Zika virus transmissions, which may change flavivirus epidemiology and expand the geographical range to territories with no insect vectors. It is unknown whether JEV has tropism in the female lower reproductive tract and the potential for sexual transmission in humans. While clinical outcomes of transplacental JEV infection are described in humans and pigs, cellular ta

SUBMITTER: Chapagain S 

PROVIDER: S-EPMC9337681 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature