CoLoRd: compressing long reads.

ABSTRACT: The cost of maintaining exabytes of data produced by sequencing experiments every year has become a major issue in today's genomic research. In spite of the increasing popularity of third-generation sequencing, the existing algorithms for compressing long reads exhibit a minor advantage over the general-purpose gzip. We present CoLoRd, an algorithm able to reduce the size of third-generation sequencing data by an order of magnitude without affecting the accuracy of downstream analyses.

SUBMITTER: Kokot M 

PROVIDER: S-EPMC9337911 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature